Human Structure Virtual Histology
    Nerve Tissue
     
     

    Ganglia are collections of cell bodies outside the CNS for sensory or autonomic nerves. Outside of the spinal cord (this slide is from thoracic level 6) or on this slide, locate and examine a spinal or dorsal root ganglion. Identify:

    • Large sensory neurons (N)
    • Satellite cells (S, glial cells) surrounding each neuron
    • Connective tissue (CT) covering the entire ganglion

    Examine a sympathetic ganglion on this slide, and identify the same structures just found in the sensory ganglion.

     

     

    Clinical note: The herpes zoster virus, acquired during childhood chicken pox, can remain dormant in neurons of sensory ganglia. The virus can be reactivated in older individuals, migrating along axons to the skin and producing blisters and a painful rash known as shingles. Although skin symptoms usually heal within weeks, the pain (post-herpetic neuralgia) may persist for many months.

     

     

    Smaller parasympathetic ganglia are found in the walls of organs in the digestive tract where they function to regulate contraction of smooth muscle. Examine the image at the right and these slides of esophagus and intestine) to locate parasympathetic ganglia with their large neuronal cell bodies surrounded by satellite cells.
     

     

    Now let's look at peripheral nerves.