Golgi apparatus is a group of flattened membranous cisternae formed from vesicles that pinch off of the ER and coalesce.

• Polypeptides in the cisternae are glycosylated and otherwise modified in the Golgi complex.
• At the “maturing” face of the Golgi, new vesicles pinch off and are sorted to different destinations according to their contents.
• Most Golgi vesicles either condense to form secretory granules that release their contents by exocytosis or remain in the cytoplasm as lysosomes or peroxisomes.
• The Golgi is generally difficult to see by LM, but examine the TEM image to see its makeup.

• In certain cell types that are specialized for secretion, such as the glandular epithelium of the anterior pituitary gland, sometimes the Golgi can be visualized as a clear space near the nucleus (arrows).

Lysosomes are next.